Abstract
Preamble. Myocardial revascularization with coronary artery bypass grafting (CABG) and percutaneous
interventions on coronary arteries in many cases allow one to improve life quality of
the patients with ischemic heart disease (IHD) and in some cases improve the prognosis.
However invasive approaches for IHD treatment can preserve their effect only with constant use
of optimal medication (OM) based on contemporary clinical recommendations for the secondary
IHD prophylaxis to prevent the progression of atherosclerotic process. It is essential to
assess the expedience of the physician-patient organizing programs (training, telephone interviews,
intensive outpatient follow-up) after coronary artery bypass grafting or CABG combined
with the left ventricle (LV) reconstructive surgeries for aneurysm.
Material and methods. The study includes 196 patients after myocardial revascularization procedure,
randomized into two groups: intervention group including structured training and outpatient
follow-up and control group.
Results. The use of the individual programs results in lethality rate reduction, allows one to
reduce repeated hospitalizations need significantly, attain regress of Va chronic heart failure
functional class (CHF FC) during the whole first year period and in more short periods (within
3 months), facilitates tolerance to exercise stress, evaluated with 6-min. objective test, has a positive
effect on linear and volumetric indices of LV function within 12 months as compared to
standard therapy.
Significant improvement of the life quality in the IHD patients participating in the optimized
multifactor program is noted during the first year, in more early dates than with conventional
therapy.
Conclusion. It was revealed that within 12 months this approach would allow one to bring nearer
the therapy carried out in the outpatient setting to the treatment according to the recommendations
based on scientifically proved data. It improves quality of life according to most
scores compared to real clinical practice.
References
Бокерия Л. А. Влияние оптимизированного многофакторного подхода к лечению больных ИБС после прямой реваскуляризации миокарда на качество жизни и потребность в госпитализациях (результаты 3-месячного рандомизированного клинического исследования) / Л. А. Бокерия, М. М. Алшибая, Н. Г. Бенделиани, С. Ф. Никонов // Клин. физиол. кровообращ. - 2011. - № 3. - С. 5-16.
Орлов В. А. Влияние терапевтического обучения больных с выраженной хронической сердечной недостаточностью на качество их жизни и потребность в повторных госпитализациях: результаты 12-месячного рандомизированного исследования / В. А. Орлов, С. Р. Гиляревский, О. А. Боева и др. // Кардиология. - 2002. - № 5. - С. 56-61.
Bramlage, P. The effect of optimal medical therapy on 1-year mortality after acute myocardial infarction / P. Bramlage, C. Messer, N. Bitterlich at al. // Heart. - 2010. - Vol. 96. - P. 604-609.
Denton, T. A. Secondary prevention after coronary bypass: the American Heart Association
Williams, J. Secondary prevention after coronary artery bypass graft surgery findings of a National randomized controlled trial and sustained society-led incorporation into practice / J. Williams, E. R. DeLong, E. D. Peterson et al. for the Society of Thoracic Surgeons and the National Cardiac Database // Circulation. - 2011. - Vol. 123. - P. 39-45.