Abstract
Objective. Study of myocardial functional state, remodeling peculiarities of the left ventricle
(LV) and mitral valve apparatus in IHD patients with mitral regurgitation progression following
operation for isolated coronary artery bypass grafting (CABG) and CABG in combination
with LV surgical reconstruction.
Materials and methods. Analysis of 101 IHD patients who had surgical treatment was carried
out during the study. The analysis was carried out in 4 groups of patients: 1A group (40
patients) - after isolated CABG without mitral insufficiency (MI) progression, without regurgitation
or with moderate regurgitation, 1B group (17 patients) - after isolated CABG with
MI progression up to significant rate; 2A group (30 patients) - after CABG and surgical
reconstruction of the LV postinfarction aneurysm without MI progression or with its moderate
rate; 2B group (14 patients) - following CABG and LV surgical reconstruction with MI progression
up to significant rate.
Results. It was shown that the leading mechanism of mitral regurgitation progression is development
of LV remodeling (local and global) leading to papillary muscles displacement, tension
and restrictive movement of mitral valve leaflets and their incompetent coaptation. Categories
of patients with high risk of MR progression after surgical treatment were determined.
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