Abstract
Introduction. Currently the problems of advisability and indications for performing endarterectomy from common and external carotid artery for internal
carotid artery occlusion are poorly covered in the available literature. The objective of the present article is to determine the indications, feasibility of
this operation and to evaluate its long-term outcomes.
Materials and methods. The study group comprised 72 patients who underwent internal carotid artery resection with the reconstruction of external carotid
artery. The control group consisted of 52 patients with transient ischemic attack caused by internal carotid artery atherosclerotic occlusive disease and
those patients refused surgical treatment. The evaluation of treatment results was carried out during intra- and early (up to 1 month) and late postoperative
(up to 1 year) periods. The dynamics of clinical condition and patients’ quality of life was assessed on the basis of European Quality of Life 5
Dimensions Questionnaire (EQ-5D).
Results. The total number of long-term complications in the study group was more than 4 times less than in the control group (p<0.001). Recurrence of
acute cerebrovascular disorder was registered in 2 (3.3 %) cases. The number of cases of recurrent acute cerebrovascular disorder in homolateral circulation
was 7 times more than in the study group and were registered in 14 (26.9 %) patients.
Surgical treatment proved to be more efficient for symptomatic patients than for asymptomatic patients. After internal carotid artery resection with
endarterectomy and external carotid artery reconstruction the overall quality of life increased in as little as 1 month according to the clinical assessment
made by the visual analogue scale.
Most indicators showed the improvement of quality of life after surgical treatment which continued for 6 months and remained stable for 1 year.
Conclusion. Internal carotid artery resection with endarterectomy and external carotid artery reconstruction is characterized by the stable positive influence
on the majority of indicators of quality of life of patients with internal carotid artery occlusive disease compared to medical treatment during oneyear
observation.
References
1. Archi J.P. Jr., Engrinton R.D. Carotid Surgery. In: Vascular surgery highligts 1999–2000 / Ed. A.H. Davies, A.W.M. Mitchell. Oxford:
Health press; 2000: 61–8.
2. Парфенов В.Е., Свистов Д.В. Хирургическое лечение атеросклеротических поражений артерий каротидного бассейна
(диагностика, показания, противопоказания, перспектива). В кн.: Сборник лекций по актуальным вопросам
нейрохирургии. М.: Элби; 2008.
3. Transcranial Doppler sonography / Ed. R. Aaslid. Wien–New-York: Springer; 1986.
4. Терновой С.К., Синицын В.Е. Спиральная компьютерная и электронно-лучевая томография. М.: Видар; 2003.
5. Bleiweis M.S., Georgiou D., Brundage B.H. Detection of intracardiac masses by ultrafast computed tomography. J. Comput. Assist.
Tomogr. 1993; 17 (1): 42–5.
6. Katz D.A., Marks M.P., Napel S.A. et al. Circle of Willis: eval uation with spiral CT angiography, MR angiography and conventional
angiography. Radiology. 1995; 195 (2): 445–9.
7. Klingenbeck-Regn K., Schaller S., Flohr T. et al. Subsecond multi-slice computed tomography: basics and applications. Eur. J.
Radiol. 1999; 31: 110–24.
8. Schellinger P.D., Jansen O., Jochen B. et al. A standardized MRI stroke protocol comparison with CT in hyperacute intracerebral
hemorrhage. Stroke. 1999; 30: 765–8.
9. Зайцев А.Ю., Щербюк А.Н., Артюхина Е.Г. и др. Новые методы диагностики и лечения облитерирующих заболеваний
магистральных артерий. Медицинская помощь. 2004; 3: 3–13.
10. Гусев Е.И., Бойко А.Н., Кольяк Е.В. Вклад нарушений микроциркуляции в формирование клинической картины
рассеянного склероза у больных старше 45 лет и возможные направления коррекции сосудистой патологии. Журнал
неврологии и психиатрии им. С.С. Корсакова. 2008; 108: 25–31.
11. Martнnez Fernбndez R., Silva Y., Gуmez E. Carotid endarterectomy: description, results and clinic evolution in 100 consecutive
symptomatic patients. Neurologia. 2010; 24 (6): 391–8.
12. Powers W.J., Derdeyn C.P., Fritsch S.M. et al. Benign prognosis of never-symptomatic carotid occlusion. Neurology. 2000; 54:
878–82.
13. Adams H.P. Jr., Bendixen В.Н., Kappelle L.J. et al. Classification of subtype of acute ischemic stroke: Definitions for use in a multicenter
clinical trial: TOAST: Trial of Org 10172 in Acute Stroke Treatment. Stroke. 1993; 24: 35–41.
14. Лаврентьев А.В. Микрохирургическая реваскуляризация головного мозга: Дис. … д-ра мед. наук. М.; 2000.
15. Basso Candy J.A. Carotid artery stenosis end endarterectomy. J. AORN. 2002; 75: 310–24.
16. Fields W.S., Lemat N.A. Joint study of extracranial arterial occlusion, X: internal carotid artery occlusions. JAMA. 1976; 235:
2734–8.
17. Кандыба Д.В., Сокуренко Г.Ю. Нарушения мозгового кровообращения при патологии экстракраниальных артерий. СПб.;
2003.