Abstract
The key factors, defining the prognosis for the patients with cardiac failure are heart remodeling and myocar
dial contractility. New methods of myocardial visualization gave the unprecedented impulse to the research
in the areas of heart physiology and pathophysiology. However in the clinical practice these methods are still
rarely used, although the numbers of the indices and areas of usage are growing with each year. Systolic and
diastolic functions evaluation based on Tissue Doppler and 2D and 3D Speckle tracking provides with the
left ventricular filling pressure and enables to carry out the differential diagnostics between the constrictive
pericardium and myocardium diseases with diastolic disfunction and dyspnea, caused by cardiac and extra
cardiac causes. It also helps to understand the physiology of the systolic and diastolic cardiac insufficiency,
disturbance of the left ventricle pumping function. It also lets us monitor the respond to the treatment among
the patients with cardiac insufficiency. Myocardial function analysis gives an opportunity to carry out diag
nostics at an early stage, detect asymptotic dysfunction of the left ventricle, to detect dyssynchrony and to
forecast the respond to the resynchronisation therapy. This article sums up the indicators of the systolic and
diastolic malfunction along with various types of pathology. In addition the evaluation of the mechanical dis-
synchrony with the aid of TD and 2D and 3D Speckle image tracking was carried out. The aim of this ar-
ticle is the summary of available data and knowledge on the determination of myocardium function, what
with no doubts is important for the used in clinical practice and understanding of the development of the
above method in the future.
References
1.
Lower R.
Tractatus de Corde. London: Oxford
University Press; 1669.
2.
Arts T., Hunter W.C., Douglas A.S.
et al.
Macroscopic three-dimensional motion patterns of
the left ventricle.
Adv. Exp. Med. Biol.
1993; 346:
383-92.
3.
Hansen D.E., Daughters G.T. 2nd, Alderman E.L.
et al. Torsional deformation of the left ventricular
midwall in human hearts with intramyocardial
markers.
Circ. Res.
1988; 62: 941-52.
4.
Bell S.P., Nyland L., Tischler M.D.
et al.
Alterations in the determinants of diastolic suction
during pacing tachycardia.
Circ. Res.
2000; 87:
235-40.
5.
Gorman J.H. 3rd, Gupta K.B., Streicher J.T.
et al.
Dynamic three-dimensional imaging of the mitral
valve and left ventricle by rapid sonomicrometry array localization.
J. Thorac. Cardiovasc. Surg.
1996; 112: 712-26.
6.
Buchalter M.B., Weiss J.L., Rogers W.J.
et al.
Noninvasive quantification of left ventricular rota
tional deformation in normal humans using mag
netic resonance imaging myocardial tagging.
Circulation.
1990; 81: 1236-44.
7.
Kim H.K., Sohn D.W., Lee S.E.
et al. Assessment of
left ventricular rotation and torsion with two
dimensional speckle tracking echocardiography.
J. Am. Soc.Echocardiogr.
2007; 20: 45-53.
8.
Yoshida T., Mori M., Nimura Y.
et al. Analysis of
heart motion with ultrasonic Doppler method and its
clinical application.
Am. Heart J.
1961; 61: 61-75.
9.
Yoshitoshi Y., Machii K., Tomachi G.
et al. Doppler
measurement of mitral valve and ventricular wall
velocities.
Ultrasonics.
1966; 4: 27-8.
10.
Kostis J.B., Mavrogeorgis E., Slater A.
et al. Use of a
range-gated, pulsed ultrasonic Doppler technique
for continuous measurement of velocity of the pos
terior heart wall.
Chest.
1972; 62 (5): 597-604.
11.
Sonnenblick E.H., Parmley W.W., Urschel C.W.
et al. Ventricular function: evaluation of myocardial
contractility in health and disease.
Prog. Cardiovasc.
Dis.
1970; 27: 449-66.
12.
McDicken W.M., SutherlandG.R., Moran C.M.et
al.
Colour Doppler velocity imaging of the myocardi
um.
Ultrasound Med. Biol.
1992; 18: 651-4.
13.
Miyatake K., Yamagishi M., Tanaka N.
et al. New
method for evaluating left ventricular wall motion
by color-coded tissue Doppler imaging: in vitro and
in vivo studies.
J. Am. Coll. Cardiol.
1995. 25:
717-24.
14.
Fleming A.D., Xia X., McDicken W.M.
et al.
Myocardial velocity gradients detected by Doppler
imaging.
Br. J. Radiol.
1994; 67: 679-88.
15.
Uematsu M., Miyatake K., Tanaka N.
et al.
Myocardial velocity gradient as a new indicator of
regional left ventricular contraction: detection by a
two-dimensional tissue Doppler imaging technique.
J. Am. Coll. Cardiol.
1995; 26 (1): 217-23.
16.
Gorcsan III J., Gulati V., Mandarino W.
et al. Color-
coded measures of myocardial velocity throughout
the cardiac cycle by tissue Doppler imaging to
quantify regional left ventricular function.
Am.
Heart J.
1996; 131: 1203-13.
17.
Derumeaux G., Ovize M., Loufoua J.
et al. Doppler
tissue imaging quantitates regional wall motion du
ring myocardial ischemia and reperfusion.
Circulation.
1998; 97: 1970-7.
18.
Wilkenshoff U.M., Sovany A., Wigstrom L.
et al.
Regional mean systolic myocardial velocity estima
tion by real-time color Doppler myocardial ima
ging: a new technique for quantifying regional sys
tolic function.
J. Am. Soc. Echocardiogr.
1998; 11:
683-92.
19.
Heimdal A., Stoylen A., Torp H.
et al. Real-time
strain rate imaging of the left ventricle by ultra
sound.
J. Am. Soc. Echocardiogr.
1998; 11: 1013-9.
20.
George R., SutherlandK., LivHatle M.
et al. Doppler
myocardial imaging: A textbook. Brussels: Hasselt;
2006: 322.
21.
Алёхин М.Н.
Тканевой допплер в клинической
эхокардиографии. М.; 2005.
22.
Какучая Т.Т.
Тканевой допплер, деформация и
скорость деформации миокарда в оценке функции миокарда - концептуальные технические
основы и применение в клинике.
Креативная
кардиология.
2008; 1: 73-93.
23.
Mor-Avi V., Lang R.M., Badano L.P.
et al. Current
and evolving echocardiographic techniques for the
quantitative evaluation of cardiac mechanics:
ASE/EAE consensus statement on methodology
and indications endorsed by the Japanese Society of
Echocardiography.
J. Am. Soc. Echocardiogr.
2011;
24 (3): 277-313.
24.
Алёхин М.Н.
Ультразвуковые методики оценки
деформации миокарда и их клиническое значе
ние. Двухмерное отслеживание пятен серой
шкалы ультразвукового изображения миокарда
в оценке его деформации и скручивания (лек
ция 2).
Ультразвуковая и функциональная диаг
ностика.
2011; 3: 107-20.
25.
Алёхин М.Н.
Ультразвуковые методики оценки
деформации миокарда и их клиническое значе
ние. Допплеровская визуализация тканей в
оценке деформации миокарда (лекция 1).
Уль
тразвуковая и функциональная диагностика.
2011; 1: 105-17.
26.
Yoshihiro S., Satoshi Y., Takeshi A.
et al. Speckle
Tracking imaging for the Assessment of cardiac
Resynchronization Therapy (START) Study.
Circulation.
2012; 126: A17041.
27.
Henson R.E., SongS.K., Pastorek J.S.
et al. Left ven
tricular torsion is equal in mice and humans.
Am. J.
Physiol. Heart Circ. Physiol.
2000; 278: 1117-23.
28.
Carasso S., Biaggi P., Rakowski H.
et al. Velocity
Vector Imaging: Standard Tissue-tracking Results
Acquired In Normals - the VVI- STRAIN study.
J. Am. Soc. Echocardiogr.
2012; 25 (5): 543-52.
29.
Хадзегова А.Б., Васюк Ю.А., Ющук Е.Н., Габито
ва Р.Г.
Оценка деформации миокарда с помо
щью технологии speckle tracking у больных ар
териальной гипертензией.
Сердце.
2011; 2 (10):
118-25.
30.
Feigenbaum H., Armstrong W.F., Ryan T.
Feingenbaum's echocardiography. USA:
Lippincote; 2005.
31.
Skulstad H., Urheim S., Edvardsen T.
et al. Grading
of myocardial dysfunction by tissue Doppler
echocardiography: a comparison between velocity,
displacement, and strain imaging in acute ischemia.
J. Am. Coll. Cardiol.
2006; 47: 1672-82.
32.
Covell J.W.
Tissue structure and ventricular wall
mechanics.
Circulation.
2008; 118: 699-701.
33.
Marwick T.H., Leano R.L., Brown J.
et al.
Myocardial strain measurement with 2-dimensional
speckle-tracking echocardiography: definition of
normal range.
JACC Cardiovasc. Imaging.
2009; 2:
80-4.
34.
Moore C.C., Lugo-Olivieri C.H., McVeigh E.R.
et al.
Three-dimensional systolic strain patterns in the
normal human left ventricle: characterization with
tagged MR imaging.
Radiology
. 2000; 213: 453-66.
35.
Edvardsen T., Gerber B.L., Garot J.
et al.
Quantitative assessment of intrinsic regional
myocardial deformation by Doppler strain rate
echocardiography in humans: validation against
three-dimensional tagged magnetic resonance
imaging.
Circulation.
2002; 106: 50-6.
36.
Kowalski M., Kukulski T., Jamal F.
et al. Can natu
ral strain and strain rate quantify regional myocardial deformation? A study in healthy subjects.
Ultrasound Med. Biol.
2001; 27: 1087—97.
37.
Sun J.P., Popovic Z.B., Greenberg N.L.
et al. Non
invasive quantification of regional myocardial func
tion using Doppler-derived velocity, displacement,
strain rate, and strain in healthy volunteers: effects
of aging.
J. Am. Soc. Echocardiogr.
2004; 17: 132—8