Abstract
Objective. To present the results of autopsy observations of the cor triatriatum dexter (CTD) in combination with severe, complex congenital heart defects.
Material and methods. We have studied 5 drugs with CTD (age of patients 1.8 to 1.2 years, average weight of 9.4 to 5.2 kg, average height of 71.2 to 18.2 cm, gender ratio of men and women 3:2). The structural features of the heart are described, the morphometry is carried out; histological study of membrane was conducted on slices 4–5 microns thick with hematoxilin-eosine coloration and by Weigert for elastic fibers.
Results. In all cases there was situs solitus, the presence of an atrial septal communication in the form of an open foramen ovale or atrial septal defect. The absence of the right atrioventricular communication was in 4 cases and in 1 there was hypoplasia of tricuspid valve. The concomitant anomalies included ventricular septal defect, a combination of valve stenosis and coarctation of the aorta with patent ductus arteriosus, additional left-sided vena cava superior, valve stenosis and hypoplasia of pulmonary artery.
Conclusion. Anatomical variants of CTD are represented by a membrane without perforation, a membrane with 1 hole, a probing mobile membrane with 2 or more perforations. Histologically, the membrane is a valve-like effect of connective tissue dysplasia.
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About the authors
- Margarita V. Gordeeva, Cand. Med. Sc., Senior Researcher, Pathologist; orcid.org/0000-0002-4348-3220
- Roman A. Serov, Dr. Med. Sc., Professor, Head of Pathological Anatomy Department; orcid.org/0000-0002-7962-7273
- Elena A. Pomazanova, Junior Researcher; orcid.org/0000-0002-6693-6077
- Anna E. Zharikova, Junior Researcher; orcid.org/0000-0002-9135-2671
- Leo A. Bockeria, Dr. Med. Sc., Professor, Academician of Russian Academy of Sciences and Russian Academy of Medical Sciences, Director; orcid.org/0000-0002-6180-2619
