Abstract
Objective: definition operative tactics of correction concomitant tricuspid insufficiency in aortic stenosis.
Material and methods. In meta-analysis included 1513 patients with isolated aortic stenosis and concomitant tricuspid insufficiency. Literature search of all articles carried out in the following databases from January 2000 to may 2017: PubMed and Medscape. Statistical analysis was performed by comparing 2 groups of patients: I group – patients with isolated aortic stenosis and concomitant tricuspid regurgitation 2+ (severe) (n=253) and II group – patients with isolated aortic stenosis and concomitant tricuspid regurgitation up to 2nd degree (n=1260). Statistical analysis was performed using Excel and Statistica 7.0.
Results. Mortality rate was statistically significantly higher in the 1st group – 29.6% (68 patients) versus 15% (175 patients) in group II. In the late postoperative period, in both groups there was a slight progression of tricuspid insufficiency (2.2±0.7 in the I group and 1.3±0.6 in the 2 group, p<0.001). The influence of the following risk factors on the progression of residual tricuspid regurgitation was established: atrial fibrillation, the presence of a pacemaker, concomitant mitral insufficiency and the severity of left ventricular hypertrophy.
Conclusion. According to the results of the study, in determining the operative tactics of concomitant tricuspid insufficiency, in addition to the main indications (recommendations), it is necessary to pay attention to the presence of atrial fibrillation, previously implanted with pacemakers, the presence of concomitant mitral insufficiency and the severity of left ventricular hypertrophy.
References
-
Rodés-Cabau J., Taramasso M., O'Gara P.T. Diagnosis
and treatment of tricuspid valve disease: current and
future perspectives. Lancet. 2016; 388: 2431–42. DOI:
10.1016/S0140-6736(16)00740-6
- Izumi C., Miyake M., Takahashi S., Matsutani H.,
Hashiwada S., Kuwano K. et al. Progression of isolated
tricuspid regurgitation late after left-sided valve surgery,
clinical features and mechanisms. Circulation. 2011; 75:
2902–7. DOI: 10.1253/circj.CJ-11-0718
- Kwak J.J., Kim Y.J., Kim M.K., Kim H.K., Park J.S.,
Kim K.H. et al. Development of tricuspid regurgitation
late after left-sided valve surgery: a single-center experience
with long-term echocardiographic examinations.
Am. Heart J. 2008; 155: 732–7. DOI: 10.1016/j.ahj.2007.11.010
- Mahesh B., Wells F., Nashef S., Nair S. Role of concomitant
tricuspid surgery in moderate functional tricuspid
regurgitation in patients undergoing left heart
valve surgery. Eur. J. Cardiothorac. Surg. 2013; 43: 2–8.
DOI: 10.1093/ejcts/ezs441
- Taramasso M., Vanermen H., Maisano F., Guidotti A.,
La Canna G., Alfieri O. The growing clinical importance
of secondary tricuspid regurgitation. J. Am. Coll.
Cardiol. 2012; 59: 703–10. DOI: 10.1016/j.jacc.2011.09.069
- Tornos Mas P., Rodrıguez-Palomares J.F., Antunes M.J.
Secondary tricuspid valve regurgitation: a forgotten
entity. Heart Br. Card. Soc. 2015; 101: 1840–8. DOI:
10.1136/heartjnl-2014-307252
- Arsalan M., Walther T., Smith R.L., Grayburn P.A.
Tricuspid regurgitation diagnosis and treatment. Eur.
Heart J. 2017; 38 (9): 634–8. DOI: 10.1093/eurheartj/ehv487
- Song H., Kim M.J., Chung C.H., Choo S.J., Song M.G.
et al. Factors associated with development of late significant
tricuspid regurgitation after successful left-sided
valve surgery. Heart. 2009; 95: 931–6. DOI: 10.1136/hrt.2008.152793
- De Meester P., Van De Bruaene A., Herijgers P.,
Voigt J.U., Budts W. Tricuspid valve regurgitation:
Prevalence and relationship with different types of heart
disease. Acta. Cardiol. 2012; 67: 549–56. DOI: 10.2143/AC.67.5.2174129
- Nishimura R.A., Otto C.M., Bonow R.O., Carabello
B.A., Erwin J.P., Guyton R.A. et al. 2014 AHA/ACC
guideline for the management of patients with valvular
heart disease: a report of the American College of
Cardiology/American Heart Association Task Force on
Practice Guidelines. J. Am. Coll. Cardiol. 2014; 63:
57–185. DOI: 10.1016/j.jacc.2014.02.536
- Vahanian A., Alfieri O., Andreotti F., Antunes M.J.,
Barón-Esquivias G., Baumgartner H. et al. Guidelines
on the management of valvular heart disease (version
2012): the joint task force on the management of valvular
heart disease of the European Society of Cardiology
(ESC) and the European Association for Cardio-
Thoracic Surgery (EACTS). Eur. J. Cardiothorac. Surg.
2012; 42: 1–44. DOI: 10.1093/eurheartj/ehs109
- Lindman B.R., Maniar H.S., Jaber W.A., Lerakis S.,
Mack M.J., Suri R.M. et al. The effect of tricuspid
regurgitation and the right heart on survival after transcatheter
aortic valve replacement: Insights from the
PARTNER II inoperable cohort. Circ. Cardiovasc.
Interv. 2015; 8 (4): 002073. DOI: 10.1161/CIRCINTERVENTIONS.114.002073
- Takashi Igarashi, Masahiro Tanji, Koki Takahashi,
Keiichi Ishida, Satomi Sasaki, Hitoshi Yokoyama.
Predictive factor of secondary tricuspid regurgitation
after aortic valve replacement for aortic stenosis: the
importance of myocardial hypertrophy and diastolic
dysfunction. Gen. Thorac. Cardiovasc. Surg. 2017; 65:
259–66. DOI: 10.1007/s11748-017-0748-2
- Jeong D.S., Sung K., Kim W.S., Lee Y.T., Yang J.H.,
Jun T.G. et al. Fate of functional tricuspid regurgitation
in aortic stenosis after aortic valve replacement.
J. Thorac. Cardiovasc. Surg. 2014; 148: 1328–33.e1.
DOI: 10.1016/j.jtcvs.2013.10.056.
- Dumont C., Galli E., Oger E., Fournet M., Flecher E.,
Leclercq Ch. et al. Pre- and postoperative tricuspid
regurgitation in patients with severe symptomatic aortic
stenosis: importance of pre-operative tricuspid annulus
diameter. Eur. Heart J. 2017; 0: 1–10. DOI:
10.1093/ehjci/jex031
- Mascherbauer J., Kammerlander A.A., Marzluf B.A.,
Graf A., Kocher A., Bonderman D. Prognostic impact
of tricuspid regurgitation in patients undergoing aortic
valve surgery for aortic stenosis. PLoS One. 2015; 10 (8):
e0136024. DOI: 10.1371/journal.pone.0136024
- Miglioranza M.H., Mihaila S., Muraru D., Cucchini
U., Iliceto S., Badano L.P. Dynamic changes in tricuspid
annular diameter measurement in relation to the
echocardiographic view and timing during the cardiac
cycle. J. Am. Soc. Echocardiogr. 2015; 28: 226–35. DOI:
10.1016/j.echo.2014.09.017
- Miglioranza M.H., Mihaila S., Muraru D., Cucchini
U., Iliceto S., Badano L.P. Variability of tricuspid
annulus diameter measurement in healthy volunteers.
JACC Cardiovasc. Imaging. 2015; 8: 864–6. DOI:
10.1016/ j.jcmg.2014.09.010
- Dreyfus G.D., Martin R.P., Chan K.M.J., Dulguerov
F., Alexandrescu C. Functional tricuspid regurgitation.
J. Am. Coll. Cardiol. 2015; 65: 2331–6. DOI:
10.1016/j.jacc.2015.04.011
- Gillinov A.M., Gelijns A.C., Parides M.K., DeRose J.J. Jr,
Moskowitz A.J., Voisine P. Surgical ablation of atrial
fibrillation during mitral-valve surgery. N. Engl. J. Med.
2015; 372: 1399–409. DOI: 10.1056/NEJMoa1500528
- Gelsomino S., La Meir M., Van Breugel H.N.A.M.,
Renzulli A., Rostagno C., Lorusso R. Surgical ablation
in patients undergoing mitral valve surgery: impact of
lesion set and surgical techniques on long-term success.
Europace. 2016; 18: 1528–37. DOI: 10.1093/europace/euv402
- Mascherbauer J., Maurer G. The forgotten valve:
lessons to be learned in tricuspid regurgitation. Eur.
Heart J. 2010; 31 (23): 2841–3. DOI: 10.1093/eurheartj/ehq303
- Pagnesi M., Montalto C., Mangieri A., Agricola E.,
Puri R., Chiarito M. et al. Tricuspid annuloplasty versus
a conservative approach in patients with functional
tricuspid regurgitation undergoing left-sided heart
valve surgery: A study-level meta-analysis. Int. J.
Cardiol. 2017; 240: 138–44. DOI: 10.1016/j.ijcard.2017.05.014
- Yarbrough W.M., Mukherjee R., Ikonomidis J.S.,
Zile M.R., Spinale F.G. Myocardial remodeling with
aortic stenosis and after aortic valve replacement:
mechanisms and future prognostic implications.
J. Thorac. Cardiovasc. Surg. 2012; 143: 656. DOI:
10.1016/j.jtcvs.2011.04.044
- Weidemann F., Herrmann S., Störk S., Niemann M.,
Frantz S., Lange V. et al. Impact of myocardial
fbrosis in patients with symptomatic severe aortic
stenosis. Circulation. 2009; 120: 577. DOI: 10.1161/CIRCULATIONAHA.108.847772
About the authors
- Skopin Ivan Ivanovich, Dr. Med. Sc., Professor, Head of Department, Director of Institute for Coronary and Vascular Surgery; orcid.org/0000-0001-7411-202X
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Latyshev Mikhail Sergeevich, Postgraduate; orcid.org/0000-0003-1771-4264
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Vavilov Aleksandr Vladimirovich, Cardiovascular Surgeon; orcid.org/0000-0002-0488-5630
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Asatryan Tigran Vladimirovich, Researcher; orcid.org/0000-0002-0141-5481
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Dremin Aleksandr Valentinovich, Junior Researcher; orcid.org/0000-0003-3036-9493