Abstract
Papillary fibroelastomas are extremely rare primary cardiac tumors. Mainly, the pathological process is localized on the cusps of the aortic and mitral valves, much less often the tricuspid valve is affected. There is practically no information on the diagnosis and treatment of papillary pulmonary valve fibroelastoma. We present a clinical case of a 60-years old female patient. She was admitted to our hospital with an accidental find, a volumetric mass was clearly visualized using three-dimensional transthoracic echocardiography, which was subsequently confirmed by intraoperative data and the results of histological examination. Moreover, 3D TEE let us define the size of the tumour and its structure more accurately. Due to a high level of mobility of the tumour and the risk of embolic complications the patient was surged at Bakoulev National Medical Research Center for Cardiovascular Surgery. The surgery was operated with full tumour resection and the valve function was sustained.
References
- Serov R.A., Kavsadze V.E., Gogichaishvili I.K., Bockeria L.A. Papillary fibroelastoma of the heart. Patho-morphology and morphogenesis. Bulletin of Bakoulev Center. Cardiovascular Diseases. 2005; 6 (5): 49–57 (in Russ.).
- Hakim F.A., Aryal M.R., Pandit A., Pandit A.A., Alegria J.R., Kendall C.B., Click R.L. Papillary fibroelastoma of the pulmonary valve – a systematic review. Echocardiography. 2013; 31 (2): 234–40. DOI: 10.1111/echo.12388
- Bockeria L.A., Skopin I.I., Serov R.A., Mironenko V.A., Spirin L.V. Papillary fibroelastoma in the pathology of the heart valves. Bulletin of Bakoulev Center. Cardiovascular Diseases. 2018; 9 (6, appl.): 29 (in Russ.).
- Tamin S.S., Maleszewski J.J., Scott C.G., Khan S.K., Edwards W.D., Bruce Ch.J. et al. Prognostic and bioepidemiologic implications of papillary fibroelastomas. J. Am. Coll. Cardiol. 2015; 65 (22): 2420–9. DOI: 10.1016/j.jacc.2015.03.569
- Guo D.-C., Yang Y.-H., Liu Y., Sun L.-L., Zhu W.-W., Lu Z., Li Y.-D. Incidental finding of an asymptomatic pulmonary valve papillary fibroelastoma: A case report. J. Clin. Ultrasound. 2019; 47 (9): 568–71. DOI: 10.1002/jcu.22768
- Nomoto N., Tani T., Konda T., Kim K., Kitai T., Ota M. et al. Primary and metastatic cardiac tumors: echo- 694The Bulletin of Bakoulev Center. Cardiovascular Diseases. 2021; 22 (6) DOI: 10.24022/1810-0694-2021-22-6-688-694 Brief reports cardiographic diagnosis, treatment and prognosis in a 15-years single center study. J. Cardiothorac. Surg. 2017; 12 (1). DOI: 10.1186/s13019-017-0672-7
- Otto C.M. Textbook of clinical echocardiography. 5th edn. Philadelphia, PA.: Elsevier Saunders; 2013.
- Atlas of 3D Echocardiography. Ed. by E.A. Gill. Philadelphia, PA.: Elsevier Saunders; 2013.
- Palaskas N., Thompson K., Gladish G., Agha A.M., Hassan S., Iliescuc C. et al. Evaluation and management of cardiac tumors. Curr. Treat. Options Cardiovasc. Med. 2018; 20 (4): 29. DOI: 10.1007/s11936-018-0625-z
- Daveron E., Jain N., Kelley G.P., Luer W.H., Fermin C., Helmcke F., Kerut E.K. Papillary fibroelastoma and lambl’s excrescences: Echocardiographic diagnosis and differential diagnosis. Echocardiography. 2005; 22 (5): 461–3. DOI: 10.1111/j.1540-8175.2005.40063.x
- Tamin S.S., Maleszewski J.J., Scott C.G., Khan S.K., Edwards W.D., Bruce C.S. et al. Prognostic and bioepidemiologic implications of papillary fibroelastomas. J. Am. Coll. Cardiol. 2015; 65: 2420–9. DOI: 10.1016/j.jacc.2015.03.569
- Gowda R.M., Khan I.A., Nair C.K., Mehta N.J., Vasavada B.C., Sacchi T.J. Cardiac papillary fibroelastoma: a comprehensive analysis of 725 cases. Am. Heart J. 2003; 146: 404–10. DOI: 10.1016/S0002-8703(03) 00249-7
- Рафаели Т.Р., Исаева И.В., Попов Р.Ю., Рогатова А.Н., Степанов А.В., Барац Л.С. др. Папиллярная фиброэластома (успешное удаление редкой формы папиллярной фиброэластомы клапана легочной артерии). Международный журнал интервенционной кардиоангиологии. 2014; 37: 44–8.
- Mete A., Erbasan O., Kemaloglu C., Ozbudak I., Turkay C. Pulmonary artery obstruction due to papillary fibroelastoma on the pulmonary valve: A rare cardiac tumor. Thorac. Cardiovasc. Surg. 2009; 57 (02): 116–8. DOI: 10.1055/s-2008-1038726
About the authors
- Marina Yu. Mironenko, Cand. Med. Sci., Head of Department; ORCID
- Igor’ Ya. Klimchuk, Cand. Med. Sci., Cardiac Surgeon; ORCID
- Marianna Yu. Nazranova, Ultrasound Diagnostics Resident; ORCID
- Leo A. Bockeria, Academician of the Russian Academy of Sciences and Russian Academy of Medical Sciences, President; ORCID
