Abstract
Chronic thromboembolic pulmonary hypertension (CTEPH) is a disease of obstructive remodeling of the pulmonary arteries as a result of thromboembolism of large vessels. It is known that the average frequency of CTEPH is 0.1–9.1% during the first 2 years after a symptomatic event of pulmonary embolism. The large margin of error is likely due to bias in the assessment, the paucity of early symptoms, and the difficulty in differentiating acute pulmonary embolism from the symptoms of preexisting CTEPH. In the differential diagnosis of CTEPH, it is necessary to take into account and treat the following conditions in accordance with the accumulated clinical cases to date. These conditions include pulmonary sarcoma, tumor cell embolism, parasitic invasion, foreign body embolism, and congenital or acquired pulmonary artery stenosis. Modern experience shows that it is most rational in the treatment of CTEPH to use an integrated approach of a combination of thrombendarterectomy from the pulmonary artery in proximal lesions with subsequent stage-wise transluminal balloon angioplasty of the distal bed.
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About the authors
- Sergey V. Gorbachevskiy, Dr. Med. Sci., Professor, Head of Department of Surgical Treatment of Heart Diseases with Progressive Pulmonary Hypertension; ORCID
- Komoliddin Kh. Rakhmonov, Cand. Med. Sci., Cardiovascular Surgeon; ORCID
- Amirullo A. Sabitov, Cardiovascular Surgeon; ORCID
