Abstract
Biological markers are an important element in the algorithms for diagnosis, risk stratification and prognosis in patients with heart failure. Recognized markers – natriuretic peptides – has a number of limitations, and in recent years many new substances have appeared – which are considered as candidates for biomarkers of heart failure. One of the most promising biomarkers of “mechanical” myocardial stress is soluble ST2, and this review discussing the possibility of using ST2 in clinical practice in patients with ischemic heart failure. This review and clinical case is devoted to discussing the possibility of using soluble ST2 as a biomarker of heart failure for the purpose of diagnosis, assessing the prospects for revascularization, stratifying the risk of negative events, assessing the prognosis and effectiveness of treatment in patients with LV ischemic dysfunction.
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About the authors
- Rashid N. Songurov, Cardiologist; ORCID
- Inna V. Koksheneva, Dr. Med. Sci., Senior Researcher; ORCID
- Rustam M. Ibragimov, Cand. Med. Sci., Researcher; ORCID
- Viktor P. Alimov, Cardiologist; ORCID
- El’vina F. Tugeeva, Dr. Med. Sci., Senior Researcher; ORCID
- Yuriy I. Buziashvili, Dr. Med. Sci., Professor, Academician of RAS, Head of Department; ORCID